Investigating the feasibility of tumour molecular profiling in gastrointestinal malignancies in routine clinical practice.

doi:10.1093/annonc/mdx631

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Article

Investigating the feasibility of tumour molecular profiling in gastrointestinal malignancies in routine clinical practice.

Annals of oncology : official journal of the European Society for Medical Oncology - 1 Jan 2018

Moorcraft S Y, Gonzalez de Castro D, Cunningham D, Jones T, Walker B A, Peckitt C, Yuan L C, Frampton M, Begum R, Eltahir Z, Wotherspoon A, Teixeira Mendes L S, Hulkki Wilson S, Gillbanks A, Baratelli C, Fotiadis N, Patel A, Braconi C, Valeri N, Gerlinger M, Rao S, Watkins D, Chau I, Starling N

Abstract excerpt

Background: Targeted capture sequencing can potentially facilitate precision medicine, but the feasibility of this approach in gastrointestinal (GI) malignancies is unknown. Patients and methods: The FOrMAT (Feasibility of a Molecular Characterisation Approach to Treatment) study was a feasibility study enrolling patients with advanced GI malignancies from February 2014 to November 2015. Targeted capture...

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PMID: 29361134
DOI: 10.1093/annonc/mdx631

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BRAF
KRAS

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