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Clinical Utility of Genomic Profiling Tests in Patients with Advanced Gastrointestinal Cancers.

Targeted oncology - 1 Mar 2022

Takeda Hiroyuki, Imoto Kiyomi, Umemoto Kumiko, Doi Ayako, Arai Hiroyuki, Horie Yoshiki, Mizukami Takuro, Oguri Tomoyo, Ogura Takashi, Izawa Naoki, Yamamoto Hiroyuki, Yamano Yoshihisa, Sunakawa Yu

Abstract excerpt

BACKGROUND: Comprehensive analyses of cancer-related genomic alterations are expected to lead to increased availability of targeted therapies. However, in patients with gastrointestinal (GI) cancers, the utility of genomic profiling is unclear because of common non-druggable alterations and rapid disease progression that prevent a sufficient time period to seek targets. OBJECTIVE: The aim of this study was to...

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Biomarkers, Tumor
Gastrointestinal Neoplasms
Mutation
Proto-Oncogene Proteins B-raf

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PMID: 35366174
DOI: 10.1007/s11523-022-00871-4

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