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Clinical impact of panel gene sequencing on therapy of advanced cancers of the digestive system: a retrospective, single center study.

BMC cancer - 25 Apr 2024

Dreikhausen Lena, Klupsch Anna, Wiest Isabella, Xiao Qiyun, Schulte Nadine, Betge Johannes, Boch Tobias, Brochhausen Christoph, Gaiser Timo, Hofheinz Ralf-Dieter, Ebert Matthias, Zhan Tianzuo

Abstract excerpt

BACKGROUND: Panel gene sequencing is an established diagnostic tool for precision oncology of solid tumors, but its utility for the treatment of cancers of the digestive system in clinical routine is less well documented. METHODS: We retrospectively identified patients with advanced or metastatic gastrointestinal, pancreaticobiliary or hepatic cancers who received panel gene sequencing at a tertiary university...

Topics

Humans
Female
Male
Retrospective Studies
Middle Aged
Aged
Adult
Aged, 80 and over
Young Adult
Digestive System Neoplasms
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Precision Medicine

Molecular Targeted Therapy

Biomarkers, Tumor

Source

Open in PubMed Open full text

Identifiers

PMID: 38664720
DOI: 10.1186/s12885-024-12261-2
PMCID: PMC11046933

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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