Article
Assessing the clinical value of targeted massively parallel sequencing in a longitudinal, prospective population-based study of cancer patients.
British journal of cancer - 14 Apr 2015
Wong S Q, Fellowes A, Doig K, Ellul J, Bosma T J, Irwin D, Vedururu R, Tan A Y-C, Weiss J, Chan K S, Lucas M, Thomas D M, Dobrovic A, Parisot J P, Fox S B
Abstract excerpt
INTRODUCTION: Recent discoveries in cancer research have revealed a plethora of clinically actionable mutations that provide therapeutic, prognostic and predictive benefit to patients. The feasibility of screening mutations as part of the routine clinical care of patients remains relatively unexplored as the demonstration of massively parallel sequencing (MPS) of tumours in the general population is required to...
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