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Article

The Mutational Landscape of Gastrointestinal Malignancies as Reflected by Circulating Tumor DNA.

Molecular cancer therapeutics - 1 Jan 2018

Riviere Paul, Fanta Paul T, Ikeda Sadakatsu, Baumgartner Joel, Heestand Gregory M, Kurzrock Razelle

Abstract excerpt

We aimed to assess the utility of a novel, noninvasive method of detecting genomic alterations in patients with gastrointestinal malignancies, i.e., the use of liquid biopsies to obtain blood-derived circulating tumor DNA (ctDNA) through an analysis of the genomic landscape of ctDNA (68 genes) from 213 patients with advanced gastrointestinal cancers. The most common cancer types were colorectal adenocarcinoma (N...

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Source

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Identifiers

PMID: 29133621
DOI: 10.1158/1535-7163.MCT-17-0360
PMCID: PMC5752585

Genes

KRAS
EGFR
MYC

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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