Article
Association of maternal KIR gene content polymorphisms with reduction in perinatal transmission of HIV-1.
PloS one - 1 Jan 2018
Omosun Yusuf O, Blackstock Anna J, Williamson John, van Eijk Anne Maria, Ayisi John, Otieno Juliana, Lal Renu B, Ter Kuile Feiko O, Slutsker Laurence, Shi Ya Ping
Abstract excerpt
The role of killer cell immunoglobulin-like receptors (KIRs) in the transmission of HIV-1 has not been extensively studied. Here, we investigated the association of KIR gene content polymorphisms with perinatal HIV-1 transmission. The KIR gene family comprising 16 genes was genotyped in 313 HIV-1 positive Kenyan mothers paired with their infants. Gene content polymorphisms were presented as presence of individual...
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