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Article

Killer Cell Immunoglobulin-Like Receptor Alleles Alter HIV Disease in Children.

PloS one - 1 Jan 2016

Singh Kumud K, Qin Min, Brummel Sean S, Angelidou Konstantia, Trout Rodney N, Fenton Terence, Spector Stephen A

Abstract excerpt

BACKGROUND: HLA class I molecules are ligands for killer cell immunoglobin like receptors (KIR) that control the antiviral response of natural killer (NK) cells. However, the effects of KIR and HLA (KIR/HLA) alleles on HIV disease of children have not been studied. METHODS: 993 antiretroviral naïve children with symptomatic HIV infection from PACTG protocols P152 and P300 were genotyped for KIR and HLA alleles...

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Share to CD4 Lymphocyte Count
Share to CD4-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Progression

Share to HIV Infections

Share to HLA Antigens

Share to Infant

Share to Killer Cells, Natural

Share to Receptors, KIR

Source

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Identifiers

PMID: 26983081
DOI: 10.1371/journal.pone.0151364
PMCID: PMC4794224

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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