Article
KIR Gene Content Diversity in a Zimbabwean Population: Does KIR2DL2 Have a Role in Protection Against Human Immunodeficiency Virus Infection?
Omics : a journal of integrative biology - 1 Dec 2016
Mhandire Kudakwashe, Zijenah Lynn Sodai, Yindom Louis-Marie, Duri Kerina, Mlambo Tommy, Tshabalala Mqondisi, Mazengera Lovemore Ronald, Mhandire Doreen Zvipo, Musarurwa Cuthbert, Dandara Collet, Rowland-Jones Sarah, Matarira Hilda Tendisa, Stray-Pedersen Babill
Abstract excerpt
Killer cell immunoglobulin-like receptors (KIRs) mediate natural killer cell function through interaction with their cognate human leukocyte antigen ligands. Thus, KIR gene variants have been implicated in resistance or susceptibility to viral infections. However, research on the role of these variants remains contradictory and inconclusive. In the present study, we investigated KIR gene content diversity and its...
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