Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Establishment of the early cilia preassembly protein complex during motile ciliogenesis.

Proceedings of the National Academy of Sciences of the United States of America - 6 Feb 2018

Horani Amjad, Ustione Alessandro, Huang Tao, Firth Amy L, Pan Jiehong, Gunsten Sean P, Haspel Jeffrey A, Piston David W, Brody Steven L

Abstract excerpt

Motile cilia are characterized by dynein motor units, which preassemble in the cytoplasm before trafficking into the cilia. Proteins required for dynein preassembly were discovered by finding human mutations that result in absent ciliary motors, but little is known about their expression, function, or interactions. By monitoring ciliogenesis in primary airway epithelial cells and MCIDAS-regulated induced...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Surface
Share to Axonemal Dyneins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to GTP-Binding Proteins

Share to Induced Pluripotent Stem Cells

Share to Microtubule-Associated Proteins

Share to Proteins

Share to Respiratory Mucosa

Source

Open in PubMed Open full text

Identifiers

PMID: 29358401
DOI: 10.1073/pnas.1715915115
PMCID: PMC5819421

Genes

SPAG1
DNAAF2
MCIDAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Establishment of the early cilia preassembly protein complex during motile ciliogenesis.PMID 29358401Read ↗

HEATR2 plays a conserved role in assembly of the ciliary motile apparatus.Semantic proximity Read ↗

Whole-exome capture and sequencing identifies HEATR2 mutation as a cause of primary ciliary dyskinesia.Semantic proximity Read ↗

ATMIN is a transcriptional regulator of both lung morphogenesis and ciliogenesis.Semantic proximity Read ↗

Functional partitioning of a liquid-like organelle during assembly of axonemal dyneinsSemantic proximity Read ↗

CEP55 promotes cilia disassembly through stabilizing Aurora A kinase.Semantic proximity Read ↗

Liver Disease Reveals KIF12 as a Critical Regulator of Mitochondria, Lysosome and Cilia LocalizationSemantic proximity Read ↗

Drosophila Ttc12 genes are putative co-chaperones for dynein assembly and docking in motile ciliaSemantic proximity Read ↗

Crystal structure of human PACRG in complex with MEIG1Semantic proximity Read ↗

A phase separated organelle at the root of motile ciliopathySemantic proximity Read ↗

The role of SPAG1 in the assembly of axonemal dyneins in human airway epithelia.Semantic proximity Read ↗

Centrosome and ciliary abnormalities in fetal akinesia deformation sequence human fibroblastsSemantic proximity Read ↗

Roles for CEP170 in cilia function and dynein-2 assemblySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.