Article

Crystal structure of human PACRG in complex with MEIG1

2019-09-27

Abstract excerpt

In human, the Parkin Co-Regulated Gene (PACRG) shares a bidirectional promoter with Parkin, a gene involved in Parkinson’s disease, mitochondrial quality control and inflammation. The PACRG protein is essential to the formation of the inner junction between doublet microtubules of the axoneme, a structure found in flagella and cilia. PACRG interacts with tubulin as well as the meiosis expressed gene 1 (MEIG1) prot...

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Literature Corpus work: ad556955-92c6-5479-84a8-ba9d5e94a82a
DOI: 10.1101/783373

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