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Article

Conditionally reprogrammed cells (CRC) methodology does not allow the in vitro expansion of patient-derived primary and metastatic lung cancer cells.

International journal of cancer - 1 Jul 2018

Sette Giovanni, Salvati Valentina, Giordani Ilenia, Pilozzi Emanuela, Quacquarini Denise, Duranti Enrico, De Nicola Francesca, Pallocca Matteo, Fanciulli Maurizio, Falchi Mario, Pallini Roberto, De Maria Ruggero, Eramo Adriana

Abstract excerpt

Availability of tumor and non-tumor patient-derived models would promote the development of more effective therapeutics for non-small cell lung cancer (NSCLC). Recently, conditionally reprogrammed cells (CRC) methodology demonstrated exceptional potential for the expansion of epithelial cells from patient tissues. However, the possibility to expand patient-derived lung cancer cells using CRC protocols is...

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Identifiers

PMID: 29341112
DOI: 10.1002/ijc.31260

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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