Article
Inferring cell state by quantitative motility analysis reveals a dynamic state system and broken detailed balance.
PLoS computational biology - 1 Jan 2018
Kimmel Jacob C, Chang Amy Y, Brack Andrew S, Marshall Wallace F
Abstract excerpt
Cell populations display heterogeneous and dynamic phenotypic states at multiple scales. Similar to molecular features commonly used to explore cell heterogeneity, cell behavior is a rich phenotypic space that may allow for identification of relevant cell states. Inference of cell state from cell behavior across a time course may enable the investigation of dynamics of transitions between heterogeneous cell...
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