Article
Image-Based Tracking of Heterogeneous Single-Cell Phenotypes.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018
Patsch Katherin, Mumenthaler Shannon M, Ruderman Daniel
Abstract excerpt
Cells display broad heterogeneity across multiple phenotypic features, including motility, morphology, and cell signaling. Live-cell imaging techniques are beginning to capture the importance and interdependence of these phenomena. However, existing image analysis pipelines often fail to capture the intricate changes that occur in small subpopulations, either due to poor segmentation protocols or cell tracking...
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