Article
Quantifying landscape-flux via single-cell transcriptomics uncovers the underlying mechanism of cell cycle
2023-08-03
Abstract excerpt
Recent developments in single-cell sequencing technology enable the acquisition of the whole transcriptome data. However, understanding the underlying mechanism and identifying the driving force of the transcriptional regulation of the cell function directly from these data remains challenging. To address this urgent need, we reconstruct a continuous vector field of cell cycle based on the discrete single-cell RNA...
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Identifiers and source
- Literature Corpus work
- 122224d1-3368-5dc6-b556-04fca062acca
- DOI
- 10.1101/2023.08.01.551525
