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Quantifying landscape-flux via single-cell transcriptomics uncovers the underlying mechanism of cell cycle

2023-08-03

Abstract excerpt

Recent developments in single-cell sequencing technology enable the acquisition of the whole transcriptome data. However, understanding the underlying mechanism and identifying the driving force of the transcriptional regulation of the cell function directly from these data remains challenging. To address this urgent need, we reconstruct a continuous vector field of cell cycle based on the discrete single-cell RNA...

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Literature Corpus work
122224d1-3368-5dc6-b556-04fca062acca
DOI
10.1101/2023.08.01.551525
Open publication

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Quantifying landscape-flux via single-cell transcriptomics uncovers the underlying mechanism of cell cycleDOI 10.1101/2023.08.01.551525
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