Article
Age-related differences of genetic susceptibility to patients with acute lymphoblastic leukemia.
Aging - 23 Apr 2021
Hao Qing, Cao Minyuan, Zhang Chunlan, Yin Dandan, Wang Yuelan, Ye Yuanxin, Zhao Shan, Yang Yunfan, Chen Ke-Ling, Ying Binwu, Wang Lanlan, Zhang Yiguan, Xu Caigang, Zhu Yiping, Wu Yu, Gao Ju, Zhao Jun-Ning, Zhang Yan, Lu Xiaoxi
Abstract excerpt
Inherited predispositions to acute lymphoblastic leukemia have been well investigated in pediatric patients, but studies on adults, particularly Chinese patients, are limited. In this study, we conducted a genome-wide association study in 466 all-age Chinese patients with Acute lymphoblastic leukemia (ALL) and 1,466 non-ALL controls to estimate the impact of age on ALL susceptibility in the Chinese population....
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