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Article

Reprogramming neurodegeneration in the big data era.

Current opinion in neurobiology - 1 Feb 2018

Zhou Lujia, Verstreken Patrik

Abstract excerpt

Recent genome-wide association studies (GWAS) have identified numerous genetic risk variants for late-onset Alzheimer's disease (AD) and Parkinson's disease (PD). However, deciphering the functional consequences of GWAS data is challenging due to a lack of reliable model systems to study the genetic variants that are often of low penetrance and non-coding identities. Pluripotent stem cell (PSC) technologies offer...

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PMID: 29331684
DOI: 10.1016/j.conb.2017.12.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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