Article

The complete genome of the KOLF2.1J reference iPSC line

2026-03-09

Abstract excerpt

While induced pluripotent stem cells (iPSCs) have gained popularity in studying neurodegenerative diseases, the heterogeneity of stem cells used across studies impacts cross-study comparison. The iPSC Neurodegenerative Disease Initiative (iNDI) selected the KOLF2.1J cell line and prioritized its use as a reference standard for studying the effects of pathogenic variants on cell biology due to its stability and neu...

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Literature Corpus work: 2a116b7d-88cb-578d-ac39-d03aea86f223
DOI: 10.64898/2026.03.06.710144

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