Article
Distribution of CYP2C19*17 allele and genotypes in an Indian population.
Journal of clinical pharmacy and therapeutics - 1 Jun 2012
Anichavezhi D, Chakradhara Rao U S, Shewade D G, Krishnamoorthy R, Adithan C
Abstract excerpt
WHAT IS KNOWN AND OBJECTIVE: CYP2C19*17 allele increases the metabolic activity of CYP2C19 resulting in decreased therapeutic levels of CYP2C19 substrates. There exist inter-ethnic differences in the distribution of this allele. The present study was aimed at establishing the allele and genotype frequencies of CYP2C19*17 in a South Indian Tamilian population. Furthermore, we describe the haplotype structure of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
