Article
Genetic Colorectal Cancer and Adenoma Risk Variants Are Associated with Increasing Cumulative Adenoma Counts.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Nov 2020
Sullivan Brian A, Qin Xuejun, Redding Thomas S, Gellad Ziad F, Stone Anjanette, Weiss David, Madison Ashton N, Sims Kellie J, Williams Christina D, Lieberman David, Hauser Elizabeth R, Provenzale Dawn
Abstract excerpt
BACKGROUND: The genetic basis for most individuals with high cumulative lifetime colonic adenomas is unknown. We investigated associations between known colorectal cancer-risk single-nucleotide polymorphisms (SNP) and increasing cumulative adenoma counts. METHODS: The Cooperative Studies Program #380 screening colonoscopy cohort includes 612 selected participants age 50 to 75 with genotyped blood samples and 10...
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