Article
Skin inflammation exacerbates food allergy symptoms in epicutaneously sensitized mice.
Allergy - 1 Jun 2018
Kawasaki A, Ito N, Murai H, Yasutomi M, Naiki H, Ohshima Y
Abstract excerpt
BACKGROUND: Cutaneous exposure to food antigen through impaired skin barrier has been shown to induce epicutaneous sensitization, thereby causing IgE-mediated food allergies. OBJECTIVE: We examined whether skin barrier impairment following epicutaneous sensitization exacerbates food allergies. METHODS: BALB/c mice were epicutaneously sensitized by repeated application of ovalbumin (OVA) to MC903-pretreated ear...
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