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The Epithelial Barrier Hypothesis in Food Allergies: The State of the Art

14 Mar 2025

Abstract excerpt

Recently, the "epithelial barrier hypothesis" has been proposed as a key factor in the development of allergic diseases, such as food allergies. Harmful environmental factors can damage epithelial barriers, with detrimental effects on the host immune response and on the local microbial equilibrium, resulting in chronic mucosal inflammation that perpetuates the dysfunction of the epithelial barrier. The increased...

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PMID: 40290033
DOI: 10.3390/nu17061014

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