Article
Skin barrier dysfunction and systemic sensitization to allergens through the skin.
Current drug targets. Inflammation and allergy - 1 Oct 2005
Strid Jessica, Strobel Stephan
Abstract excerpt
Most allergic, atopic and hypersensitive reactions are associated with Th2-biased immune responses and allergen-specific IgE antibodies. Pathological allergic disorders are on an alarming increase in the industrialized world. Understanding the mechanism of primary sensitization to allergens is important in elucidating the pathogenesis of these diseases and for possibly preventing their development. In this...
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