Article
Genetic variants in RORA and DNMT1 associated with cutaneous melanoma survival.
International journal of cancer - 1 Jun 2018
Li Bo, Wang Yanru, Xu Yinghui, Liu Hongliang, Bloomer Wendy, Zhu Dakai, Amos Christopher I, Fang Shenying, Lee Jeffrey E, Li Xin, Han Jiali, Wei Qingyi
Abstract excerpt
Cutaneous melanoma (CM) is considered as a steroid hormone-related malignancy. However, few studies have evaluated the roles of genetic variants encoding steroid hormone receptor genes and their related regulators (SHR-related genes) in CM-specific survival (CMSS). Here, we performed a pathway-based analysis to evaluate genetic variants of 191 SHR-related genes in 858 CMSS patients using a dataset from a...
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