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Article

Genetic variants in ELOVL2 and HSD17B12 predict melanoma-specific survival.

International journal of cancer - 15 Nov 2019

Dai Wei, Liu Hongliang, Xu Xinyuan, Ge Jie, Luo Sheng, Zhu Dakai, Amos Christopher I, Fang Shenying, Lee Jeffrey E, Li Xin, Nan Hongmei, Li Chunying, Wei Qingyi

Abstract excerpt

Fatty acids play a key role in cellular bioenergetics, membrane biosynthesis and intracellular signaling processes and thus may be involved in cancer development and progression. In the present study, we comprehensively assessed associations of 14,522 common single-nucleotide polymorphisms (SNPs) in 149 genes of the fatty-acid synthesis pathway with cutaneous melanoma disease-specific survival (CMSS). The dataset...

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17-Hydroxysteroid Dehydrogenases
Datasets as Topic
Fatty Acid Elongases
Follow-Up Studies
Kaplan-Meier Estimate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30734280
DOI: 10.1002/ijc.32194
PMCID: PMC6824721

Genes

ELOVL2
HSD17B12

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