Article
Genetic variants in PDSS1 and SLC16A6 of the ketone body metabolic pathway predict cutaneous melanoma-specific survival.
Molecular carcinogenesis - 1 Jun 2020
Dai Wei, Liu Hongliang, Chen Ka, Xu Xinyuan, Qian Danwen, Luo Sheng, Amos Christopher I, Lee Jeffrey E, Li Xin, Nan Hongmei, Li Chunying, Wei Qingyi
Abstract excerpt
A few single-nucleotide polymorphisms (SNPs) have been identified to be associated with cutaneous melanoma (CM) survival through genome-wide association studies, but stringent multiple testing corrections required for the hypothesis-free testing may have masked some true associations. Using a hypothesis-driven analysis approach, we sought to evaluate associations between SNPs in ketone body metabolic pathway...
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