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Article

Genetic variants in the folate metabolic pathway genes predict cutaneous melanoma-specific survival.

The British journal of dermatology - 1 Oct 2020

Dai W, Liu H, Liu Y, Xu X, Qian D, Luo S, Cho E, Zhu D, Amos C I, Fang S, Lee J E, Li X, Nan H, Li C, Wei Q

Abstract excerpt

BACKGROUND: Folate metabolism plays an important role in DNA methylation and nucleic acid synthesis and thus may function as a regulatory factor in cancer development. Genome-wide association studies (GWASs) have identified some single-nucleotide polymorphisms (SNPs) associated with cutaneous melanoma-specific survival (CMSS), but no SNPs were found in genes involved in the folate metabolic pathway. OBJECTIVES:...

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Identifiers

PMID: 31955403
DOI: 10.1111/bjd.18878
PMCID: PMC7367702

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