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Mutational landscape of chronic myelomonocytic leukemia in Chinese patients

24 May 2022

Abstract excerpt

BACKGROUND: Chronic myelomonocytic leukemia (CMML) is a rare and heterogeneous hematological malignancy. It has been shown that the molecular abnormalities such as ASXL1, TET2, SETBP1, and SRSF2 mutations are common in Caucasian population. METHODS: We retrospectively analyzed 178 Chinese CMML patients. The targeted next generation sequencing (NGS) was used to evaluate 114 gene variations, and the prognostic...

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PMID: 35610628
DOI: 10.1186/s40164-022-00284-z

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