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Analysis of gene mutation characteristics and its correlation with prognosis in patients with myelodysplastic syndromes.

Clinica chimica acta; international journal of clinical chemistry - 1 Feb 2024

Yang Xinyu, Zhao Hongyu, Wu Hanyang, Guo Xiaodong, Jia Hexiao, Liu Wancheng, Wei Yihong, Can Can, Ma Daoxin

Abstract excerpt

Gene mutations are a pivotal component of the pathogenesis of MDS, and they hold profound prognostic significance for predicting treatment responses and survival outcomes. However, reports about mutation patterns in Chinese MDS patients are limited. In this study, we analyzed the genetic mutation of 23 genes in 231 patients with MDS using next-generation sequencing (NGS) technology, and explored the...

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PMID: 38246208
DOI: 10.1016/j.cca.2024.117789

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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