Article
Association studies of WD repeat domain 3 and chitobiosyldiphosphodolichol beta-mannosyltransferase genes with schizophrenia in a Japanese population.
PloS one - 1 Jan 2018
Kobayashi Momoko, Jitoku Daisuke, Iwayama Yoshimi, Yamamoto Naoki, Toyota Tomoko, Suzuki Katsuaki, Kikuchi Mitsuru, Hashimoto Tasuku, Kanahara Nobuhisa, Kurumaji Akeo, Yoshikawa Takeo, Nishikawa Toru
Abstract excerpt
Schizophrenia and schizophrenia-like symptoms induced by the dopamine agonists and N-methyl-D aspartate type glutamate receptor antagonists occur only after the adolescent period. Similarly, animal models of schizophrenia by these drugs are also induced after the critical period around postnatal week three. Based upon the development-dependent onsets of these psychotomimetic effects, by using a DNA microarray...
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