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Article

Genetic analysis of the calcineurin pathway identifies members of the EGR gene family, specifically EGR3, as potential susceptibility candidates in schizophrenia.

Proceedings of the National Academy of Sciences of the United States of America - 20 Feb 2007

Yamada Kazuo, Gerber David J, Iwayama Yoshimi, Ohnishi Tetsuo, Ohba Hisako, Toyota Tomoko, Aruga Jun, Minabe Yoshio, Tonegawa Susumu, Yoshikawa Takeo

Abstract excerpt

The calcineurin cascade is central to neuronal signal transduction, and genes in this network are intriguing candidate schizophrenia susceptibility genes. To replicate and extend our previously reported association between the PPP3CC gene, encoding the calcineurin catalytic gamma-subunit, and sch...

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Source

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Identifiers

PMID: 17360599
DOI: 10.1073/pnas.0610765104
PMCID: PMC1815264

Genes

EGR3
EGR2
EGR1
EGR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17360599-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Genetic analysis of the calcineurin pathway identifies members of the EGR gene family, specifically EGR3, as potential susceptibility candidates in schizophrenia.PMID 17360599Read ↗

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