Article
Association of calcineurin A gamma subunit (PPP3CC) and early growth response 3 (EGR3) gene polymorphisms with susceptibility to schizophrenia in a Japanese population.
Psychiatry research - 30 Jan 2011
Kyogoku Chieko, Yanagi Masaya, Nishimura Kunihiro, Sugiyama Daisuke, Morinobu Akio, Fukutake Masaaki, Maeda Kiyoshi, Shirakawa Osamu, Kuno Takayoshi, Kumagai Shunichi
Abstract excerpt
To examine the association of PPP3CC (rs10108011 and rs2461491) and EGR3 (rs3750192) single-nucleotide polymorphisms (SNPs) with Japanese schizophrenia, we performed a case-control association study using 337 patients and 369 healthy controls. As a result, by our moderated cohort-size study, PPP3CC and EGR3 are not genetic risk factors for schizophrenia, whereas meta-analysis showed weak association of rs10108011...
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