Article
Investigation of genetic association between human Frizzled homolog 3 gene (FZD3) and schizophrenia: results in a Korean population and evidence from meta-analysis.
Psychiatry research - 30 Jun 2006
Jeong Seong Hoon, Joo Eun Jeong, Ahn Yong Min, Lee Kyu Young, Kim Yong Sik
Abstract excerpt
The neurodevelopmental hypothesis offers a promising approach through which to explore the pathogenesis of schizophrenia. Human Frizzled-3 protein is one of the major components of the Wnt signaling pathway and plays a crucial role in regulating early neurodevelopmental processes. Therefore, the human Frizzled homolog 3 (FZD3) gene, which encodes this protein, may be an excellent candidate gene for association...
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