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Article

Changes in Dpysl2 expression are associated with prenatally stressed rat offspring and susceptibility to schizophrenia in humans.

International journal of molecular medicine - 1 Jun 2015

Lee Hwayoung, Joo Jaesoon, Nah Seong-Su, Kim Jong Woo, Kim Hyung-Ki, Kwon Jun-Tack, Lee Hwa-Young, Kim Young Ock, Kim Hak-Jae

Abstract excerpt

Exposure to stress during critical periods of fetal brain development is an environmental risk factor for the development of schizophrenia in adult offspring. In the present study, a repeated-variable stress paradigm was applied to pregnant rats during the last week of gestation, which is analogous to the second trimester of brain development in humans. Behavioral and proteomic analyses were conducted in...

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Identifiers

PMID: 25847191
DOI: 10.3892/ijmm.2015.2161
PMCID: PMC4432923

Genes

DPYSL2

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