Article
Gene mutations in stool from gastric and colorectal neoplasia patients by next-generation sequencing.
World journal of gastroenterology - 21 Dec 2017
Youssef Omar, Sarhadi Virinder, Ehsan Homa, Böhling Tom, Carpelan-Holmström Monika, Koskensalo Selja, Puolakkainen Pauli, Kokkola Arto, Knuutila Sakari
Abstract excerpt
AIM: To study cancer hotspot mutations by next-generation sequencing (NGS) in stool DNA from patients with different gastrointestinal tract (GIT) neoplasms. METHODS: Stool samples were collected from 87 Finnish patients diagnosed with various gastric and colorectal neoplasms, including benign tumors, and from 14 healthy controls. DNA was isolated from stools by using the PSP® Spin Stool DNA Plus Kit. For each...
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