Article
Genetic Biomarker Prevalence Is Similar in Fecal Immunochemical Test Positive and Negative Colorectal Cancer Tissue.
Digestive diseases and sciences - 1 Mar 2017
Levin Theodore R, Corley Douglas A, Jensen Christopher D, Marks Amy R, Zhao Wei K, Zebrowski Alexis M, Quinn Virginia P, Browne Lawrence W, Taylor William R, Ahlquist David A, Lidgard Graham P, Berger Barry M
Abstract excerpt
BACKGROUND: Fecal immunochemical test (FIT) screening detects most asymptomatic colorectal cancers. Combining FIT screening with stool-based genetic biomarkers increases sensitivity for cancer, but whether DNA biomarkers (biomarkers) differ for cancers detected versus missed by FIT screening has not been evaluated in a community-based population. AIMS: To evaluate tissue biomarkers among Kaiser Permanente...
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