Article

PCR-based Genotyping Assays to Detect Germline APC mutations Associated with Hereditary Gastrointestinal Polyposis in Jack Russell Terriers

2020-10-22

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> The prevalence of gastrointestinal (GI) neoplastic polyps in Jack Russell Terriers (JRTs) has increased in Japan since the late 2000s. Recently, we demonstrated that JRTs with GI polyps harbor identical germline mutations in the <italic>APC </italic>gene (c.[462A>T; 463A>T]) in the heterozygous state. Thus, this disease is an autosomal dominant hereditary disord...

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Literature Corpus work: df805b58-b60f-5026-8e34-3a727ba70f25
DOI: 10.21203/rs.3.rs-94557/v1

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