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Clinical Validation of Targeted Next Generation Sequencing for Colon and Lung Cancers

14 Sept 2015

Abstract excerpt

OBJECTIVE: Recently, Next Generation Sequencing (NGS) has begun to supplant other technologies for gene mutation testing that is now required for targeted therapies. However, transfer of NGS technology to clinical daily practice requires validation. METHODS: We validated the Ion Torrent AmpliSeq Colon and Lung cancer panel interrogating 1850 hotspots in 22 genes using the Ion Torrent Personal Genome Machine....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26366557
DOI: 10.1371/journal.pone.0138245

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