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Article

The SNP rs10911021 is associated with oxidative stress in coronary heart disease patients from Pakistan.

Lipids in health and disease - 5 Jan 2018

Shahid Saleem Ullah, Shabana, Humphries Steve

Abstract excerpt

BACKGROUND: rs10911021 (a single nucleotide polymorphism present upstream of the GLUL gene) affects glutamic acid metabolism, and was shown to be associated with coronary heart disease (CHD) in patients with T2DM but a definite mechanism is unknown. It may affect glutathione cycle, an important effector in the antioxidant defense mechanism, in the cells. We checked the association of this SNP with CHD and...

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Identifiers

PMID: 29304826
DOI: 10.1186/s12944-017-0654-8
PMCID: PMC5756419

Genes

GLUL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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