Article
Association of Polymorphisms (rs 1799782, rs25489 and rs25487) in XRCC1 and (rs 13181) XPD genes with Acute Coronary Artery Syndrome in Subjects from Multan, Pakistan.
Pakistan journal of pharmaceutical sciences - 1 May 2016
Hameed Hafsa, Faryal Maemona, Aslam Muhammad Assad, Akbar Atif, Saad Abu Bakar Ali, Pasha Muhammad Burhan, Latif Muhammad, Rehan Sadiq Shaikh Rehan Rehan Sadiq Shaikh, Ali Muhammad, Iqbal Furhan
Abstract excerpt
Acute coronary artery syndrome (ACS) is the major cause of mortality in Pakistan with genetic and environmental influence on the incidence of the disease. This case-control study was designed to find out if a correlation is existing between ACS and single nucleotide polymorphisms (SNPs) in DNA repair genes XPD [at codon 751, rs 13181 (Lys to Gln)] and XRCC1 [at codon 399, rs25487 (Arg to Gln); 280, rs25489 (Arg...
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