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Article

Rad9/53BP1 protects stalled replication forks from degradation in Mec1/ATR‐defective cells

4 Jan 2018

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 29301856
DOI: 10.15252/embr.201744910

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rad9/53BP1 protects stalled replication forks from degradation in Mec1/ATR‐defective cellsPMID 29301856Read ↗

ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones.Semantic proximity Read ↗

RAD51AP1 -deficiency in vertebrate cells impairs DNA replicationSemantic proximity Read ↗

ATR and ATM differently regulate WRN to prevent DSBs at stalled replication forks and promote replication fork recoverySemantic proximity Read ↗

Replication independent ATR signalling leads to G2/M arrest requiring Nbs1, 53BP1 and MDC1.Semantic proximity Read ↗

Rad9/53BP1 promotes crossover recombination DNA repair by limiting the Sgs1 and Mph1 helicasesSemantic proximity Read ↗

Essential Function of Mec1, the Budding Yeast ATM/ATR Checkpoint-Response Kinase, in Protein HomeostasisSemantic proximity Read ↗

Mammalian RAD51 paralogs protect nascent DNA at stalled forks and mediate replication restart.Semantic proximity Read ↗

Rad51 and Mitotic Function of Mus81 are Essential for Recovery from Low-Dose of Camptothecin in the Absence of the Wrn ExonucleaseSemantic proximity Read ↗

Regulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpoint.Semantic proximity Read ↗

Mec1 and Rad53 inhibit formation of single-stranded DNA at telomeres of Saccharomyces cerevisiae cdc13-1 mutants.Semantic proximity Read ↗

Mutations in Replicative Stress Response Pathways Are Associated with S Phase-specific Defects in Nucleotide Excision Repair.Semantic proximity Read ↗

Separable roles for Mec1/ATR in genome maintenance, DNA replication, and checkpoint signaling.Semantic proximity Read ↗

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