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Article

Prioritization of potential candidate disease genes by topological similarity of protein-protein interaction network and phenotype data.

Journal of biomedical informatics - 1 Feb 2015

Luo Jiawei, Liang Shiyu

Abstract excerpt

Identifying candidate disease genes is important to improve medical care. However, this task is challenging in the post-genomic era. Several computational approaches have been proposed to prioritize potential candidate genes relying on protein-protein interaction (PPI) networks. However, the experimental PPI network is usually liable to contain a number of spurious interactions. In this paper, we construct a...

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PMID: 25460206
DOI: 10.1016/j.jbi.2014.11.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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