Article
Gene gravity-like algorithm for disease gene prediction based on phenotype-specific network.
BMC systems biology - 6 Dec 2017
Lin Limei, Yang Tinghong, Fang Ling, Yang Jian, Yang Fan, Zhao Jing
Abstract excerpt
BACKGROUND: Polygenic diseases are usually caused by the dysfunction of multiple genes. Unravelling such disease genes is crucial to fully understand the genetic landscape of diseases on molecular level. With the advent of 'omic' data era, network-based methods have prominently boosted disease gene discovery. However, how to make better use of different types of data for the prediction of disease genes remains a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.