Article
Walking on multiple disease-gene networks to prioritize candidate genes.
Journal of molecular cell biology - 1 Jun 2015
Jiang Rui
Abstract excerpt
Uncovering causal genes for human inherited diseases, as the primary step toward understanding the pathogenesis of these diseases, requires a combined analysis of genetic and genomic data. Although bioinformatics methods have been designed to prioritize candidate genes resulting from genetic linkage analysis or association studies, the coverage of both diseases and genes in existing methods is quite limited,...
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