Article
DGHNE: network enhancement-based method in identifying disease-causing genes through a heterogeneous biomedical network.
Briefings in bioinformatics - 19 Nov 2022
He Binsheng, Wang Kun, Xiang Ju, Bing Pingping, Tang Min, Tian Geng, Guo Cheng, Xu Miao, Yang Jialiang
Abstract excerpt
The identification of disease-causing genes is critical for mechanistic understanding of disease etiology and clinical manipulation in disease prevention and treatment. Yet the existing approaches in tackling this question are inadequate in accuracy and efficiency, demanding computational methods with higher identification power. Here, we proposed a new method called DGHNE to identify disease-causing genes...
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