Article
Dissecting the function of Cullin-RING ubiquitin ligase complex genes in planarian regeneration.
Developmental biology - 15 Jan 2018
Strand Nicholas S, Allen John M, Ghulam Mahjoobah, Taylor Matthew R, Munday Roma K, Carrillo Melissa, Movsesyan Artem, Zayas Ricardo M
Abstract excerpt
The ubiquitin system plays a role in nearly every aspect of eukaryotic cell biology. The enzymes responsible for transferring ubiquitin onto specific substrates are the E3 ubiquitin ligases, a large and diverse family of proteins, for which biological roles and target substrates remain largely undefined. Studies using model organisms indicate that ubiquitin signaling mediates key steps in developmental processes...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.