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Article

AIRE: a missing link to explain female susceptibility to autoimmune diseases.

Annals of the New York Academy of Sciences - 1 Jan 2018

Berrih-Aknin Sonia, Panse Rozen Le, Dragin Nadine

Abstract excerpt

Women are more susceptible to autoimmune diseases than men. Autoimmunity results from tolerance breakdown toward self-components. Recently, three transcription modulators were identified in medullary thymic epithelial cells that orchestrate immune central tolerance processes: the autoimmune regulator (AIRE), FEZ family zinc finger 2 (FEZF2 or FEZ1), and PR domain zinc finger protein 1 (PRDM1). Interestingly,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29291257
DOI: 10.1111/nyas.13529

Genes

AIRE
FEZF2
PRDM1
FEZ1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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