Escape from X Chromosome Inactivation and the Female Predominance in Autoimmune Diseases.

doi:10.3390/ijms22031114

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Escape from X Chromosome Inactivation and the Female Predominance in Autoimmune Diseases.

International journal of molecular sciences - 23 Jan 2021

Youness Ali, Miquel Charles-Henry, Guéry Jean-Charles

Abstract excerpt

Women represent 80% of people affected by autoimmune diseases. Although, many studies have demonstrated a role for sex hormone receptor signaling, particularly estrogens, in the direct regulation of innate and adaptive components of the immune system, recent data suggest that female sex hormones are not the only cause of the female predisposition to autoimmunity. Besides sex steroid hormones, growing evidence...

Topics

Animals
Autoimmune Diseases
Chromosomes, Human, X
Female
Histone Demethylases
Humans
Immunity
Intracellular Signaling Peptides and Proteins
Male
Polymorphism, Single Nucleotide
RNA, Long Noncoding
Toll-Like Receptor 7
Toll-Like Receptor 8
X Chromosome Inactivation

Source

Open in PubMed Open full text

Identifiers

PMID: 33498655
DOI: 10.3390/ijms22031114
PMCID: PMC7865432

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics