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Article

Aire in Autoimmunity.

Annual review of immunology - 1 Jun 2024

Miller Corey N, Waterfield Michael R, Gardner James M, Anderson Mark S

Abstract excerpt

The role of the autoimmune regulator (Aire) in central immune tolerance and thymic self-representation was first described more than 20 years ago, but fascinating new insights into its biology continue to emerge, particularly in the era of advanced single-cell genomics. We briefly describe the role of human genetics in the discovery of Aire, as well as insights into its function gained from genotype-phenotype...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38360547
DOI: 10.1146/annurev-immunol-090222-101050

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