Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TP53 p.R72P genotype is a marker of poor prognosis in lung cancer.

Cancer biomarkers : section A of Disease markers - 1 Jan 2018

Neumann Mirko Peter, González María Victoria, Pitiot Ana S, Santamaría Íñigo, Martínez Cristina, Tardón Adonina, Astudillo Aurora, Balbín Milagros

Abstract excerpt

BACKGROUND: Lung cancer is a leading cause of death worldwide, with poor survival rates despite diagnostic and therapeutic advances. Markers are needed in order to improve clinical patient management and survival. TP53 is frequently involved in lung cancer development with polymorphic sites potentially having a role in it. This study aims to determine the value of codon 72 missense polymorphic variant genotyping,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Carcinoma, Non-Small-Cell Lung

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease-Free Survival

Share to Kaplan-Meier Estimate

Share to Lung Neoplasms

Share to Prognosis

Share to Proportional Hazards Models

Share to Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 29286914
DOI: 10.3233/CBM-170230
PMCID: PMC13078336

Genes

TP53

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TP53 p.R72P genotype is a marker of poor prognosis in lung cancer.PMID 29286914Read ↗

The association between TP53 Arg72Pro polymorphism and lung cancer susceptibility: evidence from 30,038 subjects.Semantic proximity Read ↗

Prognostic impact of p53 Pro72 homozygous genotype in non-small cell lung cancer patients.Semantic proximity Read ↗

p53 Arg72Pro polymorphism predicts survival outcome in lung cancer patients in Indian population.Semantic proximity Read ↗

Increased risk of non-small cell lung cancer and frequency of somatic TP53 gene mutations in Pro72 carriers of TP53 Arg72Pro polymorphism.Semantic proximity Read ↗

P53 polymorphism and lung cancer susceptibility: a pooled analysis of 32 case-control studies.Semantic proximity Read ↗

The p53 codon 72 polymorphism and lung cancer risk.Semantic proximity Read ↗

Breast cancer patients with p53 Pro72 homozygous genotype have a poorer survival.Semantic proximity Read ↗

The TP53 Arg72Pro polymorphism and lung cancer risk in a population of Northern Spain.Semantic proximity Read ↗

Potential increase in the prognostic value of p53 mutation by Pro72 allele in stage I non-small-cell lung cancer.Semantic proximity Read ↗

Association of p53 codon 72 polymorphism and survival of North Indian lung cancer patients treated with platinum-based chemotherapy.Semantic proximity Read ↗

The p53 codon 72 proline allele is associated with p53 gene mutations in non-small cell lung cancer.Semantic proximity Read ↗

A meta-analysis of TP53 codon 72 polymorphism and lung cancer risk: evidence from 15,857 subjects.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.