Association of p53 codon 72 polymorphism and survival of North Indian lung cancer patients treated with platinum-based chemotherapy.

doi:10.1007/s11033-016-4072-1

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Article

Association of p53 codon 72 polymorphism and survival of North Indian lung cancer patients treated with platinum-based chemotherapy.

Molecular biology reports - 1 Dec 2016

Kumari Ankita, Bahl Charu, Singh Navneet, Behera Digambar, Sharma Siddharth

Abstract excerpt

p53 helps in maintaining genomic stability by undergoing cellular arrest, DNA repair or cellular apoptosis during DNA damage. So, as to find the association of p53Arg 72 Pro towards lung carcinogenesis and overall survival of North Indian lung cancer patients, single nucleotide polymorphic variant (rs1042522) was analyzed. 840 subjects including 420 cases and 420 controls were recruited and genotyped using...

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PMID: 27614750
DOI: 10.1007/s11033-016-4072-1

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